The main research in the Jacobs Lab focuses on understanding the genomic basis and regulatory mechanisms underlying phenotypic and developmental evolution in natural systems, and the use of large-scale population genomics to investigate rapid adaptation and eco-evolutionary processes.
Some of overarching research themes are:
i) Investigating the genomic mechanisms of intraspecific adaptive phenotypic evolution
ii) Elucidating the impact of structural genomic variation on gene regulation and adaptive evolution
iii) Determining the role gene regulatory processes, particularly alternative splicing, in rapid adaptive evolution
iv) Developing novel cost-effect sequencing approaches and analytical methods for investigate eco-evolutionary processes and fisheries management.
We moslty address these questions by integrating population genomic and functional genomic approaches in natural and experimental lab populations. We also have an interest in developing novel sequencing and analytical approaches to address diverse eco-evolutionary questions, with a focus on low-coverage whole genome sequencing.
We mainly work on fishes and other aquatic organisms, but also venture out and collaborate widely with other researchers to study adaptive processes in birds, parasites and other critters.
See below an overview of our current research themes and projects. Click on individual themes [picutres] for an overview of ongoing research projects.
Projects
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